| Date | Time | At | Opponent | Location | TV | Score |
| October 12, 2024 (Saturday) | 4:30 PM | Home | Blue-White Scrimmage (exhibition) | Chapel Hill | None | 63-53 W |
| October 15, 2024 (Tuesday) | 7 PM | Away | Memphis (exhibition) | Memphis, TN | ESPNU | 84-76 W |
| October 27, 2024 (Sunday) | 2 PM | Home | Johnson C. Smith (exhibition) | Chapel Hill | ACCNX | 127-63 W |
| November 4, 2024 (Monday) | 9 PM | Home | Elon | Chapel Hill | ACCN | 90-76 W |
| November 8, 2024 (Friday) | 7 PM | Away | Kansas | Lawrence, KS | ESPN2 | 92-89 L |
| November 15, 2024 (Friday) | 8 PM | Home | American | Chapel Hill | ACCN | 107-55 W |
| November 22, 2024 (Friday) | 1:30 AM | Away | Hawaii | Honolulu, HI | ESPN2 | 87-69 W |
| November 25, 2024 (Monday) | 11:30 PM | Away | Dayton | Lahaina, HI | ESPN2 | 92-90 W |
| November 26, 2024 (Tuesday) | 11:30 PM | Away | Auburn | Lahaina, HI | ESPN | 85-72 L |
| November 27, 2024 (Wednesday) | 9:30 PM | Away | Michigan State | Lahaina, HI | ESPN2 | 94-91 OT/L |
| December 4, 2024 (Wednesday) | 7:15 PM | Home | Alabama | Chapel Hill | ESPN | 94-79 L |
| December 7, 2024 (Saturday) | 2 PM | Home | Georgia Tech | Chapel Hill | ACCN | 68-65 W |
| December 14, 2024 (Saturday) | 4 PM | Home | La Salle | Chapel Hill | The CW | 93-67 W |
| December 17, 2024 (Tuesday) | 7 PM | Home | Florida | Charlotte, NC | ESPN | 90-84 L |
| December 21, 2024 (Saturday) | 3 PM | Away | UCLA | New York, NY | CBS | 76-74 W |
| December 29, 2024 (Monday) | 8 PM | Home | Campbell | Chapel Hill | ACCN | 97-81 W |
| January 1, 2025 (Wednesday) | 6 PM | Away | Louisville | Louisville, KY | ACCN | 83-70 L |
| January 4, 2025 (Saturday) | 12 Noon | Away | Notre Dame | South Bend, IN | CBS | 74-73 W |
| January 7, 2025 (Tuesday) | 9 PM | Home | SMU | Chapel Hill | ACCN | 82-67 W |
| January 11, 2025 (Saturday) | 4 PM | Away | NC State | Raleigh, NC | ACCN | 63-61 W |
| January 15, 2025 (Wednesday) | 7 PM | Home | California | Chapel Hill | ACCN | 79-53 W |
| January 18, 2025 (Saturday) | 2:15 PM | Home | Stanford | Chapel Hill | The CW | 72-71 L |
| January 21, 2025 (Tuesday) | 9 PM | Away | Wake Forest | Winston-Salem, NC | ESPN | 67-66 L |
| January 25, 2025 (Saturday) | 2:15 PM | Home | Boston College | Chapel Hill | The CW | 102-96 OT W |
| January 28, 2025 (Tuesday) | 9 PM | Away | Pittsburgh | Pittsburgh, PA | ESPN | 73-65 L |
| February 1, 2025 (Saturday) | 6:30 PM | Away | Duke | Durham, NC | ESPN | 87-70 L |
| February 8, 2025 (Saturday) | TBA | Home | Pittsburgh | Chapel Hill | ESPN | 67-66 W |
| February 10, 2025 (Monday) | 7 PM | Away | Clemson | Clemson, SC | ESPN | 85-65 L |
| February 15, 2025 (Saturday) | 6 PM | Away | Syracuse | Syracuse, NY | ESPN | 88-82 W |
| February 19, 2025 (Wednesday) | 7 PM | Home | NC State | Chapel Hill | ESPN | 97-73 W |
| February 22, 2025 (Saturday) | 4 PM | Home | Virginia | Chapel Hill | ESPN2 | 81-66 W |
| February 24, 2025 (Monday) | 7 PM | Away | Florida St. | Tallahassee, FL | ESPN | 96-85 W |
| March 1, 2025 (Saturday) | 12 Noon | Home | Miami | Chapel Hill | ESPN | 92-73 W |
| March 4, 2025 (Tuesday) | 7 PM | Away | Va. Tech | Blacksburg, VA | ESPN, ESPN2 | 91-59 W |
| March 8, 2025 (Saturday) | 6:30 PM | Home | Duke | Chapel Hill | ESPN | 82-69 L |
| | | | | | |